Amides

 Functional Group

The methyl groups can be replaced for any carbon chain.

Nomenclature

The suffix for amides in "-anamide".

Like other carboxylic acid derivatives, the amide is on the terminal carbon. Any other groups bound to the nitrogen atom (secondary and tertiary amides) are named as, for example, N-methyl.

N,N-dimethyl methanamide

Preparation

FROM CARBOXYLIC ACIDS

Heating is a critical step in this, to drive off the water and form the amide bond. This is called a condensation reaction.

FROM ACID CHLORIDES

Reactions

The only reaction we need to know about is hydrolysis (with an acid or a base):

Amides do not react with water. Instead, they dissolve as they can form hydrogen bonds with water molecules.